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Often times in the forums when someone has a display problem with their template and I can't replicate it from my Mac, I usually ask them for a link or a screenshot of the problem. I must say I am very surprised at the number of users who are still operating in Windows XP with ClearType disabled.
If your fonts look ragged or almost pixellated, you may be able to make your eyeballs a lot happier by turning on ClearType.